Levofloxacin Nature

Mp 218 ° C

Boiling point 572 ℃

Flash point> 110 ° (230 ° F)

Store at 0-5 ° C

Solubility chloroform: soluble10mg / mL

Color white to faint yellow

Water-soluble Slightly soluble in water or methanol. Soluble in glacial acetic acid or dichloromethane

Sensitivity

Merck 6771

CAS Database 100986-85-4 (CAS DataBase Reference)

Usage and synthesis of levofloxacin

Chemical properties Levofloxacin is ofloxacin L-body, as hemihydrate. Its solubility in water is 10 times that of the latter. Obtained from ethanol - ether needle crystallization, mp 225-227 ° C. [α] D 23-76.9 ° (C = 0.385, 0.5 mol / L sodium hydroxide solution). Acute toxicity LD50 male and female mice, male and female rats (mg / kg): 1881,1803,1478,1507 orally.

Use Levofloxacin has excellent in vitro activity, less toxic side effects than ofloxacin, safety and good pharmacokinetic properties. It can be widely used in oral or parenteral broad-spectrum fluoroquinolone antibacterials for respiratory infections, gynecological diseases, skin and soft tissue infections, surgical infections, biliary tract infections, sexually transmitted diseases and ear infections.

Use Mainly used in the manufacture of various types of levofloxacin capsules, tablets and other antibacterial agents

Use for the synthesis of antibiotics, used to treat respiratory tract, urinary tract and skin tissue infections

Henan Tianfu Chemical Co., Ltd is a high-tech enterprise, specializing in pharmaceutical intermediates, located in Zhengzhou High-tech Development Zone. We passed ISO 9001:2008 ub 2009, and won "High-tech Enterprise" by provincial government in 2013. Tianfu specializes in manufacuturing intermediates in areas such as Antitumor, Cardiocascular, central nervous system, diabetes, etc. Tianfu have established an efficient quality control system, owing standardization workshop. Also corportaes with Zhengzhou University, Henan University to establish an innovation practice base to omprove the innovatin ability.

 

Tianfu always adheres to the principle of "Live on High Quality" and puts the customer's interests first. Tianfu products have been exported to Europe and the United States, Japan, Korea, India and Latin America markets. Look forward to the future, Tianfu will keep improving the innovation ability to offer better products and service for more and more customers.