Product Name: 2,3-Dihydroxynaphthalene
Synonyms: 2,3-Dihydroxynapthalene;Naphthalene-2,3-diol;Naphthalenediol-(2,3);2,3-DIHYDROXYNAPHTHALENE;2,3-NAPHTHALENEDIOL;2,3-DIHYDROXYNAPHTHALENE, SUBL.;2 3-DIHYDROXYNAPHTHALENE 98%;2,3-DihydroxylNaphthalene
CAS: 92-44-4
MF: C10H8O2
MW: 160.17
EINECS: 202-156-7
Product Categories: Aromatics;Naphthalene derivatives;Bioactive Small Molecules;Building Blocks;Cell Biology;Chemical Synthesis;DIG-DY;Organic Building Blocks;Oxygen Compounds;Polyols
Mol File: 92-44-4.mol

2,3-Dihydroxynaphthalene Chemical Properties
Melting point  161-165 °C(lit.)
Boiling point  246.06°C (rough estimate)
density  1.0924 (rough estimate)
vapor pressure  0.8 hPa (149 °C)
refractive index  1.5178 (estimate)
Fp  175 °C
storage temp.  2-8°C
solubility  4g/l
pka 9.10±0.40(Predicted)
form  Powder
color  White to pinkish to beige-grayish
PH 6 (1g/l, H2O, 20℃)
Water Solubility  slightly soluble
BRN  742375
CAS DataBase Reference 92-44-4(CAS DataBase Reference)
NIST Chemistry Reference 2,3-Naphthalenediol(92-44-4)
EPA Substance Registry System 2,3-Naphthalenediol (92-44-4)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
RTECS  QJ4750000
F  10-23
Autoignition Temperature >330 °C
TSCA  Yes
HS Code  29072900
Toxicity LD50 orally in Rabbit: 970 mg/kg

2,3-Dihydroxynaphthalene Usage And Synthesis
Chemical Properties Off white to redish white powder
Uses 2,3-Naphthalenediol is used in cosmetics asa component of oxidative hair dye. It is usedat a concentration of <0.1%.
Health Hazard 2,3-Naphthalenediol shows low toxicity andmild irritant actions on the skin and eyes. Theoral LD50 value for rats of a 5% solutionin propylene glycol may be on the orderof 675 mg/kg (calculated by the method ofWeil). The intravenous LD50 value for miceis 56 mg/kg. At 1% concentration, it causedslight eye irritation in female albino rabbitsand exhibited erythemal response in guineapigs. At the 0.1% level (concentration in hairdye), it had no reaction on human skin. Thiscompound was nonmutagenic in Salmonellatyphimurium strain tests.
There is very little information in the literatureon the toxicity of 2,3-naphthalenediol.Assessment by the CIR expert panel on thesafety of this compound as used in cosmeticshas been inconclusive (Cosmetic, Toiletryand Fragrance Association 1987b).

Product Name: 2,3-Dihydroxynaphthalene
Synonyms: 2,3-Dihydroxynapthalene;Naphthalene-2,3-diol;Naphthalenediol-(2,3);2,3-DIHYDROXYNAPHTHALENE;2,3-NAPHTHALENEDIOL;2,3-DIHYDROXYNAPHTHALENE, SUBL.;2 3-DIHYDROXYNAPHTHALENE 98%;2,3-DihydroxylNaphthalene
CAS: 92-44-4
MF: C10H8O2
MW: 160.17
EINECS: 202-156-7
Product Categories: Aromatics;Naphthalene derivatives;Bioactive Small Molecules;Building Blocks;Cell Biology;Chemical Synthesis;DIG-DY;Organic Building Blocks;Oxygen Compounds;Polyols
Mol File: 92-44-4.mol

2,3-Dihydroxynaphthalene Chemical Properties
Melting point  161-165 °C(lit.)
Boiling point  246.06°C (rough estimate)
density  1.0924 (rough estimate)
vapor pressure  0.8 hPa (149 °C)
refractive index  1.5178 (estimate)
Fp  175 °C
storage temp.  2-8°C
solubility  4g/l
pka 9.10±0.40(Predicted)
form  Powder
color  White to pinkish to beige-grayish
PH 6 (1g/l, H2O, 20℃)
Water Solubility  slightly soluble
BRN  742375
CAS DataBase Reference 92-44-4(CAS DataBase Reference)
NIST Chemistry Reference 2,3-Naphthalenediol(92-44-4)
EPA Substance Registry System 2,3-Naphthalenediol (92-44-4)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3
RTECS  QJ4750000
F  10-23
Autoignition Temperature >330 °C
TSCA  Yes
HS Code  29072900
Toxicity LD50 orally in Rabbit: 970 mg/kg

2,3-Dihydroxynaphthalene Usage And Synthesis
Chemical Properties Off white to redish white powder
Uses 2,3-Naphthalenediol is used in cosmetics asa component of oxidative hair dye. It is usedat a concentration of <0.1%.
Health Hazard 2,3-Naphthalenediol shows low toxicity andmild irritant actions on the skin and eyes. Theoral LD50 value for rats of a 5% solutionin propylene glycol may be on the orderof 675 mg/kg (calculated by the method ofWeil). The intravenous LD50 value for miceis 56 mg/kg. At 1% concentration, it causedslight eye irritation in female albino rabbitsand exhibited erythemal response in guineapigs. At the 0.1% level (concentration in hairdye), it had no reaction on human skin. Thiscompound was nonmutagenic in Salmonellatyphimurium strain tests.
There is very little information in the literatureon the toxicity of 2,3-naphthalenediol.Assessment by the CIR expert panel on thesafety of this compound as used in cosmeticshas been inconclusive (Cosmetic, Toiletryand Fragrance Association 1987b).