Product Name: Brexpiprazole

Synonyms: Brexpiprazole(OPC34712);7-{4-[4-(1-Benzothiophen-4-yl)piperazin-1-yl]butoxy}quinolin-2(1H)-one;Brexpiprazole;OPC-34712;7-[4-(4-benzo[b]thien-4-yl-1-piperazinyl)butoxy]- 2(1H)-Quinolinone;7-[4-[4-(1-Benzothiophen-4-yl)piperazin-1-yl]butoxy]-1H-quinolin-2-one;7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one;7-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one

CAS: 913611-97-9

MF: C25H27N3O2S

MW: 433.57

EINECS: 811-628-7

Product Categories: Inhibitors;Dopamine D2 receptor partial agonist;API

Mol File: 913611-97-9.mol

Brexpiprazole Structure

Brexpiprazole Chemical Properties

Boiling point 675.2±55.0 °C(Predicted)

density 1.245±0.06 g/cm3(Predicted)

pka 11.22±0.70(Predicted)

Brexpiprazole Usage And Synthesis

Description Brexpiprazole is a kind of atypical antipsychotic. It is a dopamine D2 receptor partial agonist. As a novel serotonin-dopamine activity modulator, it can be used for the treatment of schizophrenia, and for the adjunctive treatment for depression. It can also provide efficacy and tolerability over established adjunctive treatments formajor depressive disorder(MDD).Recent study has also suggested it can ameliorate PCP-induced cognitive deficits in mice via 5-HT1A receptors.