CAS 77591-33-4 Thymosin beta 4 acetate

Product Desctiption:

CAS No.: 77591-33-4
Molecular Formula: C212H350N56O78S
Molecular Weight: 4963.49
Purity (HPLC): 98%min
Single Impurity (HPLC): 2.0%max
Amino Acid Composition: ± 10% of theoretical
Peptide Content (N%): ≥ 80.0%
Water Content(Karl Fischer): ≤ 5.0%
Acetate Content (HPIC): ≤ 15.0%
MS(ESI): Consistent
Mass Balance: 95.0~105.0%
Appearance: White powder

CAS 77591-33-4 Thymosin beta 4 acetate is a peptide which can be quite beneficial for healing of injuries, both acute and chronic, and for treatment of tendinitis. It can also improve flexibility where this has been impaired by injury, and in some cases has partially regrown lost hair. The ordinary course of treatment is 2.0 or 2.5 mg taken by injection twice per week for 4-6 weeks, followed by monthly or twice-monthly injection of 2.0 or 2.5 mg as needed.

How to use CAS 77591-33-4 Thymosin beta 4 acetate

TB-500 is typically provided as lyophilized (freeze-dried) powder in vials of 2.0 mg. A convenient amount of sterile or bacteriostatic water will be added, such as 1.0 mL. In the most common dosing protocol, the entire vial is taken at one time. If taking the entire vial, the entire amount will be drawn into a syringe, typically an insulin syringe, and injected. Injection may be subcutaneous, intramuscular, or intravenous, according to personal preference.

The most common dosing protocol is to take 2.0 or 2.5 mg of TB-500 twice per week for four to six weeks, and then reduce to a lower dosing rate such as once or twice per month for maintenance.

The body of knowledge is as yet limited with regard to TB-500 dosage. The above protocol may or may not be the most efficient, but it is the protocol with the most track record. It’s entirely possible that as knowledge is gained, method of use will change. A reasonable possibility, for example, is to increase dosing frequency to 3x/week (which I have done personally to good effect), or to increase dosing to 4 or 5 mg twice per week. Before going to such a program, however, I recommend trying the standard protocol first.

If interested in animal uses, a typical dosing protocol for horses is a course of six 10 mg injections at 7-10 day intervals. For more intensive treatment, 20 mg is used weekly. For racing dogs, a typical protocol is a course of six 5 mg injections taken weekly.

Type of water to be used with CAS 77591-33-4 Thymosin beta 4 acetate:

Plain sterile water is the most suitable diluent for CAS 77591-33-4 Thymosin beta 4 acetate. Alternatively it can be reconstituted with sterile saline (0.9% NaCl) or sterile bacteriostatic water (0.9% sodium chloride). Plain sterile water should be readily available to buy without prescription in any local pharmacy. Alternatively it can also be purchased online. It is even available on ebay.

Syringes:

The insulin type syringe with 100 markings on the side should be used. They are readily available in any local pharmacy store.

How to mix (reconstitute) the CAS 77591-33-4 Thymosin beta 4 acetate:

Pull 1ml of water into the syringe and inject it into the vial with powder. You should never shake the vial when mixing. You should not inject the water directly into the powder with force, but rather let it gently slide down the inside of the vial. If it bubbles up, you should put the vial in the refrigerator and leave it there for about 15-30 minutes. The bubbles will be gone by then. You should then gently rotate the vial between your fingers until all of the powder has dissolved (it takes about 3-4 minutes).

The vials are under vacuum, so before you can take the tb-500 out, you need to release the vacuum. Take a fresh syringe, pull air into it and inject the air into the vial (not into liquid, but into air above the liquid). This will get rid of the vacuum. You can then pull out the reconstituted tb-500 as needed.

CAS 77591-33-4 Thymosin beta 4 acetate Injection spot and procedure:

The tb-500 has a systematic effect regardless of where it is injected. Some believe that thymosin beta-4 should be injected as close to the injury as possible however there is no evidence to show this would be superior. It can be injected subcutaneously (stomach fat) or intramuscularly (shoulders, thighs, buttocks). Injections should be given in different sites (rotated) each time. Depending on the spot, you can either feel nothing or you can feel slight pain - you will learn your favorite spots in time.

Type of water to be used with CAS 77591-33-4 Thymosin beta 4 acetate:

Plain sterile water is the most suitable diluent for TB-500. Alternatively it can be reconstituted with sterile saline (0.9% NaCl) or sterile bacteriostatic water (0.9% sodium chloride). Plain sterile water should be readily available to buy without prescription in any local pharmacy. Alternatively it can also be purchased online. It is even available on ebay.

CAS 77591-33-4 Thymosin beta 4 acetate dosage and cycle duration:

Dosage depends on the purpose and severity of the injury / damage you are treating. People generally use between 4 to 8 mg of CAS 77591-33-4 Thymosin beta 4 acetate per week during the initial (loading) period of 4 to 6 weeks. Afterwards some opt to maintain the effects with a low 2 to 6 mg dose once every 2 weeks. The effects of CAS 77591-33-4 Thymosin beta 4 acetate wear off within 2 - 3 weeks of injection.

1. CAS 77591-33-4 Thymosin beta 4 acetate loading phase:
duration: between 4 - 6 weeks
dosage: between 4 - 8 mg of CAS 77591-33-4 Thymosin beta 4 acetate per week
frequency of injection:2 mg per injection, between 2 - 4 times per week (depending on the total weekly dosage)


2. CAS 77591-33-4 Thymosin beta 4 acetate maintainance phase:
duration: as long as needed
dosage: between 2 - 6 mg of CAS 77591-33-4 Thymosin beta 4 acetate per 2 weeks
frequency of injection:2 mg per injection, between 2 - 3 times per 2 weeks (depending on the total bi-weekly dosage)
 

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