Product Name: Psoralen
Synonyms: 7-furo[3,2-g][1]benzopyranone;7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE;7h-furo[3,2-g]benzopyran-7-one;FURO[3,2-G]BENZOPYRAN-7-ONE;FURO[3,2-G]COUMARIN;FICUSIN;2-Propenoic acid, 3-(6-hydroxy-5-benzofuranyl)-, delta-lactone;2-Propenoicacid,3-(6-hydroxy-5-benzofuranyl)-,δ-lactone
CAS: 66-97-7
MF: C11H6O3
MW: 186.16
EINECS: 200-639-7
Product Categories: Coumarins;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File: 66-97-7.mol

Psoralen Chemical Properties
Melting point  160-162 °C
Boiling point  280.64°C (rough estimate)
density  1.2477 (rough estimate)
refractive index  1.6310 (estimate)
storage temp.  2-8°C
form  neat
Water Solubility  65.16mg/L(25 ºC)
λmax 328nm(EtOH)(lit.)
Merck  14,7928
BRN  152784
InChIKey ZCCUUQDIBDJBTK-UHFFFAOYSA-N
CAS DataBase Reference 66-97-7(CAS DataBase Reference)
NIST Chemistry Reference 7H-furo[3,2-g][1]benzopyran-7-one(66-97-7)
Safety Information
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3
RTECS  LV0944000
F  8-10
HS Code  29339900
Hazardous Substances Data 66-97-7(Hazardous Substances Data)

Psoralen Usage And Synthesis
Description Psoralen is a kind of naturally occurring furocoumarin. It is naturally occurred in the seeds of Psoralea corylifolia as well as in the common fig, celery, parsley, West Indian Satinwood and all citrus fruits. It is capable of binding to DNA via single- and double-strand cross-linking upon photoactivation with UV radiation. It can intercalate with DNA, blocking its synthesis and cell division. For this reason, it is an important mutagen and can be used in related molecular biology studies. It also exhibits anti- proliferative, anti-allergenic and anti-histamine functions. It can also be used in PUVA treatment for skin diseases such as psoriasis, eczema and vitiligo. It is also effective tanning activator in sunscreens. Some of its derivatives, e.g. amino-psoralen, amotosalen HCl, can even inactivate pathogens in blood products.
References #
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Chemical Properties Crystalline Solid
Uses Use as photochemical probe in biological systems
Uses Psoralens are phytoalexins; they are used by plants in a defensive response to attacks by fungi and insects. They have also shown photosensitizing and phototoxic effects in animals and humans and have been used in photochemotherapy for management of vitiligo, psoriasis, and mycosis fungoides. Used as photochemical probe in biological systems.

Product Name: Psoralen
Synonyms: 7-furo[3,2-g][1]benzopyranone;7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE;7h-furo[3,2-g]benzopyran-7-one;FURO[3,2-G]BENZOPYRAN-7-ONE;FURO[3,2-G]COUMARIN;FICUSIN;2-Propenoic acid, 3-(6-hydroxy-5-benzofuranyl)-, delta-lactone;2-Propenoicacid,3-(6-hydroxy-5-benzofuranyl)-,δ-lactone
CAS: 66-97-7
MF: C11H6O3
MW: 186.16
EINECS: 200-639-7
Product Categories: Coumarins;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File: 66-97-7.mol

Psoralen Chemical Properties
Melting point  160-162 °C
Boiling point  280.64°C (rough estimate)
density  1.2477 (rough estimate)
refractive index  1.6310 (estimate)
storage temp.  2-8°C
form  neat
Water Solubility  65.16mg/L(25 ºC)
λmax 328nm(EtOH)(lit.)
Merck  14,7928
BRN  152784
InChIKey ZCCUUQDIBDJBTK-UHFFFAOYSA-N
CAS DataBase Reference 66-97-7(CAS DataBase Reference)
NIST Chemistry Reference 7H-furo[3,2-g][1]benzopyran-7-one(66-97-7)
Safety Information
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3
RTECS  LV0944000
F  8-10
HS Code  29339900
Hazardous Substances Data 66-97-7(Hazardous Substances Data)

Psoralen Usage And Synthesis
Description Psoralen is a kind of naturally occurring furocoumarin. It is naturally occurred in the seeds of Psoralea corylifolia as well as in the common fig, celery, parsley, West Indian Satinwood and all citrus fruits. It is capable of binding to DNA via single- and double-strand cross-linking upon photoactivation with UV radiation. It can intercalate with DNA, blocking its synthesis and cell division. For this reason, it is an important mutagen and can be used in related molecular biology studies. It also exhibits anti- proliferative, anti-allergenic and anti-histamine functions. It can also be used in PUVA treatment for skin diseases such as psoriasis, eczema and vitiligo. It is also effective tanning activator in sunscreens. Some of its derivatives, e.g. amino-psoralen, amotosalen HCl, can even inactivate pathogens in blood products.
References #
#
Chemical Properties Crystalline Solid
Uses Use as photochemical probe in biological systems
Uses Psoralens are phytoalexins; they are used by plants in a defensive response to attacks by fungi and insects. They have also shown photosensitizing and phototoxic effects in animals and humans and have been used in photochemotherapy for management of vitiligo, psoriasis, and mycosis fungoides. Used as photochemical probe in biological systems.