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Product Name: Yohimbine hydrochloride
Synonyms: YOHIMBINE HYDROCHLORIDE EXTRACT;Yohimban-16-alpha-carboxylic acid, 17-alpha-hydroxy, methyl ester, monohydrochloride;17alpha-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride;Yohimbine hydrochloride,99%;Yohimbine Hydrochloride (200 mg);YohiMbine hydrochloride, 99% 5GR;(16α,17α)-;YohiMbine hydrochloride API
CAS: 65-19-0
MF: C21H27ClN2O3
MW: 390.9
EINECS: 200-600-4
Product Categories: Alkaloids;Biochemistry;Indole Alkaloids;Natural Plant Extract;Adrenoceptor;Adrenoceptors;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;ADENYL;Inhibitors
Mol File: 65-19-0.mol
Yohimbine hydrochloride Structure
Yohimbine hydrochloride Chemical Properties
Melting point  288-290 °C (dec.)(lit.)
alpha  99 º (c=1%, H2O, dry subst)
refractive index  103 ° (C=1, H2O)
storage temp.  Refrigerator
solubility  H2O: 10 mg/mL
form  powder
color  white to off-white
optical activity [α]/D 100±5°, c = 1 in H2O
Sensitive  Light Sensitive
Merck  14,10102
InChIKey PIPZGJSEDRMUAW-VJDCAHTMSA-N
CAS DataBase Reference 65-19-0(CAS DataBase Reference)
EPA Substance Registry System Yohimbine hydrochloride (65-19-0)
Safety Information
Hazard Codes  T
Risk Statements  23/24/25-33-23/24
Safety Statements  22-36/37/39-45-24/25
RIDADR  UN 1544 6.1/PG 2
WGK Germany  3
RTECS  ZG1015000
TSCA  Yes
HazardClass  6.1(a)
PackingGroup  II
HS Code  29339900Chemical Properties Yohimbine hydrochloride is white to slightly yellow powder

Uses Indole alkaloid with α2-adrenergic blocking activity. Mydriatic. Used in the treatment of neurological disorders.
Uses alpha adrenergic blocker, mydriatic, antidepressant
Uses vasodilator, neuromodulator
Uses a2-adrenergic antagonist, used for erectile dysfunction
Uses Erectile dysfunction & Mydriatic agent
Uses An α2-adrenoceptor antagonist
Uses Pharmacological probe for the study of a2-adrenoceptor.
Veterinary Drugs and Treatments Yohimbine is indicated to reverse the effects of xylazine in dogs, but it is being used clinically in several other species as well.
Yohimbine may be efficacious in reversing some of the toxic effects associated with other agents (e.g., amitraz) and can be used prophylactically before amitraz dips.