Product Name: Emodin
Synonyms: Emodin, ≥80%(HPLC);6-METHYL-1,3,8-TRIHYDROXYANTHRAQUINONE;6-METHYL-1,3,8-TRIHYDROXYANTHROQUINONE;9,10-ANTHRACENEDIONE, 1,3,8-TRIHYDROXY-6-METHYL-;1,3,8-TRIHYDROXY-6-METHYL-9-10-ANTHRACENEDIONE;1,3,8-TRIHYDROXY-6-METHYLANTHRAQUINONE;emodin from frangula bark;EMODIN, TECH., 90+%
CAS: 518-82-1
MF: C15H10O5
MW: 270.24
EINECS: 208-258-8
Product Categories: Anthraquinones, Hydroquinones and Quinones;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product;Inhibitors;Frangulic acid;Anthraquinones;Hydroxyanthraquinones;Natural Plant Extract;The group of Polydatin;Protein Kinase;plant extract;Nutritional Ingredients;reference substance;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate
Mol File: 518-82-1.mol

Emodin Chemical Properties
Melting point  255 °C (dec.)(lit.)
Boiling point  373.35°C (rough estimate)
density  1.3280 (rough estimate)
refractive index  1.5000 (estimate)
storage temp.  2-8°C
solubility  DMSO: soluble
pka 6.39±0.20(Predicted)
form  powder
color  orange
Water Solubility  <0.1 g/100 mL at 19 ºC
Merck  14,3561
BRN  1888141
InChIKey RHMXXJGYXNZAPX-UHFFFAOYSA-N
CAS DataBase Reference 518-82-1(CAS DataBase Reference)
EPA Substance Registry System Emodin (518-82-1)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39-36/37
WGK Germany  3
RTECS  CB7920600
F  8-10-23
HS Code  29146990
Hazardous Substances Data 518-82-1(Hazardous Substances Data)

Emodin Usage And Synthesis
Physical and chemical properties Emodin, also known by the Chemical name 1, 3, 8-trihydroxy-6-methyl-anthraquinone with a molecular formula of C15H10O5 and a molecular weight of 270.24, exists in the form of free emodin or emodin glycosides in rhizomes and roots of Rheum palmatum L, Rheum officinale Baill, and Rheum tanguticum Maxim. ex Balf. in the family Polygonaceae. In a form of orange-yellow crystals of melting point of 256-257℃ that can sublimate under a vacuum of 1,600 Pa, the compound is soluble in ethanol, sodium hydroxide, sodium carbonate and aqueous ammonia, slightly soluble in ether, chloroform, carbon tetrachloride and benzene, and almost insoluble in water. Its form as emodin triacetate is yellow crystals of melting point of 197℃, and the form of emodin 3-methyl ether (also known as physcion) is dark-red needle crystals of melting point of 207 ℃. The compound can be obtained by chemical synthesis or by extraction from plants.
Aloe-emodin is one of the main components of aloe essential oil, present in the form of aloe-emodin in aloe, or present in the form of glycosides in rhubarb, senna and aloe.
Chemical properties Orange needles of melting point of 256-257℃ (259-260℃); soluble in alcohol, slightly soluble in ether, chloroform and benzene, and insoluble in water. The solution color would become cherry red when it is dissolved in aqueous caustic solutions, aqueous solution of sodium carbonate or ammonia solution.
Uses 1. The product can be used as a laxative. As it is susceptible to oxidative damage within the body, its diarrhea activity is actually very weak. However, it can be compounded with glucose to form a glycoside with diarrhea activity. Both emodin-1-O-β-D-glucoside and emodin-8-O-β-D-glucoside are glycosides formed through combination of emodin and glucose.  The only different between the two are the binding sites.  The two glycosides coexist in Radix et Rhizoma Rhei.
2. intermediate;health products material.

Product Name: Emodin
Synonyms: Emodin, ≥80%(HPLC);6-METHYL-1,3,8-TRIHYDROXYANTHRAQUINONE;6-METHYL-1,3,8-TRIHYDROXYANTHROQUINONE;9,10-ANTHRACENEDIONE, 1,3,8-TRIHYDROXY-6-METHYL-;1,3,8-TRIHYDROXY-6-METHYL-9-10-ANTHRACENEDIONE;1,3,8-TRIHYDROXY-6-METHYLANTHRAQUINONE;emodin from frangula bark;EMODIN, TECH., 90+%
CAS: 518-82-1
MF: C15H10O5
MW: 270.24
EINECS: 208-258-8
Product Categories: Anthraquinones, Hydroquinones and Quinones;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product;Inhibitors;Frangulic acid;Anthraquinones;Hydroxyanthraquinones;Natural Plant Extract;The group of Polydatin;Protein Kinase;plant extract;Nutritional Ingredients;reference substance;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate
Mol File: 518-82-1.mol

Emodin Chemical Properties
Melting point  255 °C (dec.)(lit.)
Boiling point  373.35°C (rough estimate)
density  1.3280 (rough estimate)
refractive index  1.5000 (estimate)
storage temp.  2-8°C
solubility  DMSO: soluble
pka 6.39±0.20(Predicted)
form  powder
color  orange
Water Solubility  <0.1 g/100 mL at 19 ºC
Merck  14,3561
BRN  1888141
InChIKey RHMXXJGYXNZAPX-UHFFFAOYSA-N
CAS DataBase Reference 518-82-1(CAS DataBase Reference)
EPA Substance Registry System Emodin (518-82-1)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39-36/37
WGK Germany  3
RTECS  CB7920600
F  8-10-23
HS Code  29146990
Hazardous Substances Data 518-82-1(Hazardous Substances Data)

Emodin Usage And Synthesis
Physical and chemical properties Emodin, also known by the Chemical name 1, 3, 8-trihydroxy-6-methyl-anthraquinone with a molecular formula of C15H10O5 and a molecular weight of 270.24, exists in the form of free emodin or emodin glycosides in rhizomes and roots of Rheum palmatum L, Rheum officinale Baill, and Rheum tanguticum Maxim. ex Balf. in the family Polygonaceae. In a form of orange-yellow crystals of melting point of 256-257℃ that can sublimate under a vacuum of 1,600 Pa, the compound is soluble in ethanol, sodium hydroxide, sodium carbonate and aqueous ammonia, slightly soluble in ether, chloroform, carbon tetrachloride and benzene, and almost insoluble in water. Its form as emodin triacetate is yellow crystals of melting point of 197℃, and the form of emodin 3-methyl ether (also known as physcion) is dark-red needle crystals of melting point of 207 ℃. The compound can be obtained by chemical synthesis or by extraction from plants.
Aloe-emodin is one of the main components of aloe essential oil, present in the form of aloe-emodin in aloe, or present in the form of glycosides in rhubarb, senna and aloe.
Chemical properties Orange needles of melting point of 256-257℃ (259-260℃); soluble in alcohol, slightly soluble in ether, chloroform and benzene, and insoluble in water. The solution color would become cherry red when it is dissolved in aqueous caustic solutions, aqueous solution of sodium carbonate or ammonia solution.
Uses 1. The product can be used as a laxative. As it is susceptible to oxidative damage within the body, its diarrhea activity is actually very weak. However, it can be compounded with glucose to form a glycoside with diarrhea activity. Both emodin-1-O-β-D-glucoside and emodin-8-O-β-D-glucoside are glycosides formed through combination of emodin and glucose.  The only different between the two are the binding sites.  The two glycosides coexist in Radix et Rhizoma Rhei.
2. intermediate;health products material.