TF CHEM - 4-Aminopyridine CAS NO.504-24-5

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Product Details

Keywords

4-Aminopyridine
504-24-5
C5H6N2

Quick Details

ProName: TF CHEM - 4-Aminopyridine
CasNo: 504-24-5
Molecular Formula: C5H6N2
Appearance: Solid
Application: Organic synthesis
DeliveryTime: PROMPT
PackAge: IN 25kg drums
Port: SHANGHAI
ProductionCapacity: 10 Metric Ton/Month
Purity: 99.0%
Storage: In Room Temperature
Transportation: As per MSDS
LimitNum: 1 Gram
Heavy metal: N/A
Grade: Industrial Grade,Food Grade,Pharma Gra...

Superiority

Henan Tianfu Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license.

We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the company is to put quality first and put our customer’s needs first - the satisfaction of our customers is the company's ultimate goal.

Improving product quality and service level is our responsibility, and creating more value for our customer’s is our purpose. We are constantly striving to make Henan Tianfu a leading chemical supplier, and hope to create a better future with you.

Details

4-Aminopyridine Basic information

Product Name: 4-Aminopyridine

Synonyms: 4-amino-pyridin;Avitrol 200;avitrol200;Compound 1861;Frampridine;mi-w-3;Phillips 1861;phillips1861

CAS: 504-24-5

MF: C5H6N2

MW: 94.11

EINECS: 207-987-9

Product Categories: Pyridine;Organics;Amines;Pyridines;Pyridines derivates;Heterocyclic Compounds;A;Alphabetical Listings;Stable Isotopes;Potassium channel;Ion Channels;amine;Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals;SERMION;Azetidines

Mol File: 504-24-5.mol

4-Aminopyridine Structure

4-Aminopyridine Chemical Properties

Melting point 157 °C

Boiling point 273 °C(lit.)

density 1.26

Fp 156°C

storage temp. 0-6°C

solubility H2O: soluble50mg/mL, clear, colorless

pka 9.114(at 25℃)

form Crystalline Powder, Solid or Crystals

color White to faint grey to light yellow

Water Solubility Soluble in water(112 g/L at 20 deg C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.

Merck 14,3933

BRN 105782

CAS DataBase Reference 504-24-5(CAS DataBase Reference)

NIST Chemistry Reference 4-Pyridinamine(504-24-5)

EPA Substance Registry System 4-Pyridinamine(504-24-5)

Safety Information

Hazard Codes T+,N,T,Xi

Risk Statements 28-36/37/38-51/53-23/24/25

Safety Statements 26-36/37/39-45-60-61-37/39-28A-1

RIDADR UN 2671 6.1/PG 2

WGK Germany 3

RTECS US1750000

F 8-21

Hazard Note Toxic/Irritant

TSCA Yes

HazardClass 6.1

PackingGroup II

HS Code 29333999

Hazardous Substances Data 504-24-5(Hazardous Substances Data)

MSDS Information

Provider Language

4-Aminopyridine English

SigmaAldrich English

ALFA English

4-Aminopyridine Usage And Synthesis

Chemical Properties WHITE TO SLIGHTLY YELLOW FINE CRYSTALLINE POWDER

Uses vasodilator

Uses Dalfampridine is used in characterizing subtypes of potassium channel, and has also been used to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults with several variations of the disease. Dalfampridine is a precursor to the drug Pinacidil.

Definition ChEBI: An aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis.

General Description White crystalline material with no odor. Used as an avicide, an intermediate and as a fixer for some textile dyes.

Reactivity Profile 4-Aminopyridine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard Material may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes. Material affects neural transmission. In sufficient concentrations, material may cause metabolic acidosis, respiratory arrest, and cardiac arrhythmias.

Fire Hazard Material may produce irritating or poisonous gases in fire. Runoff from fire control water may give off irritating or poisonous gases.

4-Aminopyridine Preparation Products And Raw materials

Preparation Products 4-ACETAMIDO-3-AMINOPYRIDINE-->(3-BROMO-PYRIDIN-4-YL)-CARBAMIC ACID TERT-BUTYL ESTER-->2,2-DIMETHYL-N-PYRIDIN-4-YL-PROPIONAMIDE-->4-(Boc-amino)pyridine-->3-PYRIDINEACETIC ACID, 4-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-A-OXO-, ETHYL ESTER-->TERT-BUTYL 3-FORMYLPYRIDIN-4-YLCARBAMATE-->efficient polymer catalyst for acrylation-synthesis and characterigation of polyamide containing supernucleophilic reagent-->4-Iodopyridine-->2-chloro-5-ethylaminomethylpyridine

Raw materials Potassium carbonate-->Pathalic acid-->Pyridine-N-oxide-->4-Nitropyridine

Henan Tianfu Chemical Co., Ltd.