China (Mainland)
Assessedsupplier
375815-87-5 Varenicline tartrate CAS NO.375815-87-5
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- 375815-87-5
- Varenicline tartrate
- 98%
Quick Details
- ProName: 375815-87-5 Varenicline tartrate
- CasNo: 375815-87-5
- Molecular Formula: C17H19N3O6
- Appearance: Powder
- Application: Pharma intermediates
- DeliveryTime: 7 days
- PackAge: 1KG -200KG Drum with pallet
- Port: Shanghai port
- ProductionCapacity: 30 Metric Ton/Month
- Purity: 98.0%Min
- Storage: Desiccate at RT
- Transportation: by sea or by air or by courier
- LimitNum: 1 Kilogram
Superiority
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.
Our main business covers the fields below:
1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis
Our advantage:
1.Higest quality and good package
2.Fast delivery
3.Better payment term
4.Fast response to customer within 6 hours
5.Good business credit in Europe ,US ,Japan ,Korea
Details
| Varenicline tartrate Basic information |
| Product Name: | Varenicline tartrate |
| Synonyms: | VARENICLINE TARTRATE;Varenicline tartrate for research;7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine (2R,3R)-2,3- dihydroxybutanedioate;Champix;CP 526555-18;6,10-Methano-6H-pyrazino(2,3-H)(3)benzazepine, 7,8,9,10-tetrahydro-, (2R,3R)-2,3-dihydroxybutanedioate (1:1);Unii-82269asb48;,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro- |
| CAS: | 375815-87-5 |
| MF: | C17H19N3O6 |
| MW: | 361.34926 |
| EINECS: | 200-659-6 |
| Product Categories: | Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;APIs;Pfizer compounds;Chantix, Champix;Inhibitors |
| Mol File: | 375815-87-5.mol |
|
|
|
| Varenicline tartrate Chemical Properties |
| Melting point | 206-208°C |
| storage temp. | Desiccate at RT |
| solubility | DMSO: >5mg/mL |
| color | white to beige |
| Safety Information |
| Hazard Codes | Xn,N,T,F |
| Risk Statements | 22-50-39/23/24/25-23/24/25-11 |
| Safety Statements | 22-57-45-36/37-16-7 |
| RIDADR | UN 3077 9 / PGIII |
| Varenicline tartrate Usage And Synthesis |
| Chemical Properties | Tan Solid |
| Uses | Nicotinic a4 acetylcholine receptor partial agonist. Aid in smoking cessation. |
| Uses | Nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation. |
| Uses | Varenicline is a prescription medication used to treat smoking addiction. Varenicline is a nicotinic receptor partial agonist. In this respect, it is similar to cytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement ther |
| Definition | ChEBI: A tartrate salt obtained by reaction of varenicline with one equivalent of (R,R)-tartaric acid. A partial agonist for nicotinic cholinergic receptors, it is used as an aid to giving up smoking. |
| Biological Activity | Orally active, subtype-selective partial agonist at α 4 β 2 nicotinic receptors (K i values are 0.06, 240, 322 and 3540 nM for α 4 β 2, α 3 β 4, α 7, α 1 β γ δ receptors respectively). Reduces nicotine-evoked dopamine release in vitro and decreases nicotine self-administration in vivo . |