China (Mainland)
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366017-09-6 Mubritinib C25H23F3N4O2 CAS NO.366017-09-6
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
- Product Details
Keywords
- Mubritinib
- 366017-09-6
- C25H23F3N4O2
Quick Details
- ProName: 366017-09-6 Mubritinib C25H23F3N4O2
- CasNo: 366017-09-6
- Molecular Formula: C25H23F3N4O2
- Appearance: white powder
- Application: Organic Chemicals
- DeliveryTime: based on your order quantity
- PackAge: based on the bulk quantity
- Port: shanghai/qingdao/dalian...
- ProductionCapacity: 10 Metric Ton/Day
- Purity: 99%
- Storage: RT
- Transportation: based on buyer's requirement
- LimitNum: 1 Metric Ton
- Grade: Industrial Grade,Food Grade,Pharma Gra...
Superiority
Mubritinib Basic information
Product Name: Mubritinib
Synonyms: MUBRITINIB;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;TAK 165;Mubritinib(TAK 165);(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole Mubritinib (TAK 165);Mubritinib 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;(E)-4-((4-(4-(1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole
CAS: 366017-09-6
MF: C25H23F3N4O2
MW: 468.47
EINECS:
Product Categories: Inhibitors
Mol File: 366017-09-6.mol
Mubritinib Structure
Mubritinib Chemical Properties
Melting point 158.0 to 162.0 °C
storage temp. Store at +4°C
Safety Information
MSDS Information
Mubritinib Usage And Synthesis
Biological Activity Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC 50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC 50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo .
Details
our company was built in 2009 with an iso certificate.in the past 5 years, we have grown up as a famous fine chemicals supplier in china
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