Doxifluridine CAS NO.3094-09-5
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- Min.Order: 1 Gram
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Keywords
- Doxifluridine
- high purity Doxifluridine
- factory supply Doxifluridine
Quick Details
- ProName: Doxifluridine
- CasNo: 3094-09-5
- Molecular Formula: C9H11FN2O5
- Appearance: White Solid
- Application: Pharmaceutical intermediates
- DeliveryTime: in stock
- PackAge: as you requested
- Port: China main port
- ProductionCapacity: 10 Kilogram/Day
- Purity: 99% min
- Storage: Room temperature
- Transportation: by courier
- LimitNum: 1 Gram
- Transportation: by courier
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Details
Product Name: | Doxifluridine |
Synonyms: | 5’-deoxy-5-fluoro-uridin;flutron;furtulon;RO-21-9738;(+)-5-FLUORO-5'-DEOXYURIDINE;5-FLUORO-5'-DEOXYURIDINE;5'-DEOXY-5-FLUOROURIDINE;5'-DEOXYFLUOROURIDINE |
CAS: | 3094-09-5 |
MF: | C9H11FN2O5 |
MW: | 246.19 |
EINECS: | 221-440-1 |
Product Categories: | Heterocycles;Pyridines, Pyrimidines, Purines and Pteredines;Pyrazines, Pyrimidines & Pyridazines;API intermediates;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Nucleotides;Intermediates & Fine Chemicals;Pharmaceuticals;Pyrazines, Pyrimidines & Pyridazines;Amines, Heterocycles, Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals;FURTULON;Anti-cancer&immunity;API |
Mol File: | 3094-09-5.mol |
Doxifluridine Chemical Properties |
Melting point | 188-192 °C(lit.) |
alpha | D25 +18.4° (c = 0.419 in water) |
refractive index | 20 ° (C=1, H2O) |
storage temp. | -20°C Freezer |
pka | 7.4(at 25℃) |
Merck | 14,3437 |
CAS DataBase Reference | 3094-09-5(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-24/25 |
WGK Germany | 2 |
RTECS | YU7526000 |
Hazard Note | Irritant |
HazardClass | IRRITANT, IRRITANT-HARMFUL |
MSDS Information |
Provider | Language |
---|---|
5-Fluoro-5′-deoxyuridine | English |
SigmaAldrich | English |
Doxifluridine Usage And Synthesis |
Chemical Properties | White Solid |
Uses | A prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity |
Uses | An antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes. A metabolite of Capecitabine |
Uses | 5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes. |
Uses | antineoplastic, pyrimidine antimetabolite |
Definition | ChEBI: A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluoro racil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase. |