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 Amoxicillin

English Synonyms D - (-) - ALPHA-AMINO-P-HYDROXYBENZYL PENICILLIN TRIHYDRATE; (2s, 5r, 6r) -6- (2-amino- AMOXICILLIN T TRIHYDRATE; AMOXICILIN TRIHYDRATE; AMOXICILLIN; AMOXYCILLIN TRIHYDRATE; (-) - 6- [2-amino-2- (2s- (2alpha, 5alpha, 6beta (s *))) - acetyl) amino) -3-dimethyl- 7-oxo-4-thia- -oxo-

CAS number: 26787-78-0

Molecular formula: C16H19N3O5S

Molecular weight: 365.4

EINECS No. 248-003-8

Antibiotics A-FAntibiotics; Chemical Structure Class; Interferes with Cell Wall Synthesis Antibiotics; Mechanism of Action; Penicillins and Cephalosporins (beta-Lactams); Spectrum of Activity; Antibacterial Drugs; Pharmaceutical intermediates; Stable isotope labeled compounds; Penicillins; Isotope labels; Small molecule inhibitors; Pharmaceutical APIs; APIs; Antibiotics; Others

Mol file: 26787-78-0.mol

Amoxicillin

Amoxicillin nature

Storage conditions 2-8 ° C

Do you have solubility information on this product that you would like to share

Merck 13,582

Stable. Incompatible with strong oxidizing agents.

CAS Database 26787-78-0 (CAS DataBase Reference)

Amoxicillin use and synthesis method

Chemical properties of white crystalline powder. The trihydrate has a melting point of 195 ° C (decomposition), solubility (mg / ml), water 4.0, methanol 7.5, absolute ethanol 3.4. The pH of the aqueous solution is about 4.7. Taste slightly bitter.

Use as a broad-spectrum semi-synthetic penicillin. Clinically for the treatment of tonsillitis, laryngitis, pneumonia, chronic bronchitis, urinary tract infections, skin and soft tissue infections, purulent pleurisy, hepatobiliary infections, sepsis, typhoid fever, dysentery and so on. The goods for the antibacterial spectrum of drugs, its role and its application are similar to that of benzylpenicillin, the advantage of low binding rate of serum protein, and blood concentrations more than twice as high as ampicillin. Amoxicillin is a good, safe and effective drug and. Developed by the British company Beecham in 1968.

Use amoxicillin is a broad-spectrum semi-synthetic penicillin antibacterial agents, its antibacterial mechanism is to interfere with the synthesis of sensitive bacterial cell wall mucobin, inhibition of bacterial metabolic enzymes, triggering the bacteria own autolytic activity, so that bacterial swelling, deformation and rupture, Dissolved death

Production methods by the 6-APA and N- (3-ethoxycarbonyl-1-methyl vinyl) p-hydroxyphenylglycine sodium salt obtained by condensation. 6-APA is an important raw material for the production of various semi-synthetic penicillins. At present, large-scale use of penicillin amidase produced by microorganisms cleaves natural penicillin (penicillin G or penicillin V).