267243-28-7 Canertinib CAS NO.267243-28-7
- FOB Price: USD: 230.00-230.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T
- Available Specifications:
A(10-150)Kilogram
- Product Details
Keywords
- 267243-28-7 Canertinib
- 267243-28-7 Canertinib
- 267243-28-7 Canertinib
Quick Details
- ProName: 267243-28-7 Canertinib
- CasNo: 267243-28-7
- Molecular Formula: C24H25ClFN5O3
- Appearance: Powder
- Application: Organic Chemicals
- DeliveryTime: according to client's demand quantity
- PackAge: as requested
- Port: SHANGHAI
- ProductionCapacity: 100 Metric Ton/Year
- Purity: 99%
- Storage: room temperature
- Transportation: by Sea
- LimitNum: 1 Kilogram
- Heavy metal: 0.01
- Grade: Industrial Grade,Pharma Grade
- Transportation: LCL
Superiority
Product Name: Canertinib
Synonyms: CI-1033 (Canertinib, PD-183805);N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide;N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]acrylamide;CI-1033(Canertinib);PD-183805;Canertinib base;Canetinib;Canertinib (CI-1033)
CAS: 267243-28-7
MF: C24H25ClFN5O3
MW: 485.944
EINECS: 1308068-626-2
Product Categories: Inhibitors
Mol File: 267243-28-7.mol
Canertinib Chemical Properties
Melting point 188-190°
Boiling point 691.0±55.0 °C(Predicted)
density 1.355±0.06 g/cm3(Predicted)
form Yellow powder.
pka 12.09±0.43(Predicted)
CAS DataBase Reference 267243-28-7
Safety Information
MSDS Information
Canertinib Usage And Synthesis
Uses Canertinib is a kind of irreversible pan-erbB tyrosine kinase inhibitor used to treat cancer.
Uses CI-1033 is a potent inhibitor of EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, respectively.
Definition ChEBI: A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a propenamido group at the 6-position, and a 3-morpholinopropoxy group at the 7-position.
4.1Description of necessary first-aid measures
If inhaled
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Following skin contact
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Following eye contact
Rinse with pure water for at least 15 minutes. Consult a doctor.
Following ingestion
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
4.2Most important symptoms/effects, acute and delayed
no data available
4.3Indication of immediate medical attention and special treatment needed, if necessary
no data available
Details
Product Name: Canertinib
Synonyms: CI-1033 (Canertinib, PD-183805);N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide;N-[4-(3-chloro-4-fluoro-anilino)-7-(3-morpholinopropoxy)quinazolin-6-yl]acrylamide;CI-1033(Canertinib);PD-183805;Canertinib base;Canetinib;Canertinib (CI-1033)
CAS: 267243-28-7
MF: C24H25ClFN5O3
MW: 485.944
EINECS: 1308068-626-2
Product Categories: Inhibitors
Mol File: 267243-28-7.mol
Canertinib Chemical Properties
Melting point 188-190°
Boiling point 691.0±55.0 °C(Predicted)
density 1.355±0.06 g/cm3(Predicted)
form Yellow powder.
pka 12.09±0.43(Predicted)
CAS DataBase Reference 267243-28-7
Safety Information
MSDS Information
Canertinib Usage And Synthesis
Uses Canertinib is a kind of irreversible pan-erbB tyrosine kinase inhibitor used to treat cancer.
Uses CI-1033 is a potent inhibitor of EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, respectively.
Definition ChEBI: A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a propenamido group at the 6-position, and a 3-morpholinopropoxy group at the 7-position.
4.1Description of necessary first-aid measures
If inhaled
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Following skin contact
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Following eye contact
Rinse with pure water for at least 15 minutes. Consult a doctor.
Following ingestion
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
4.2Most important symptoms/effects, acute and delayed
no data available
4.3Indication of immediate medical attention and special treatment needed, if necessary
no data available