China (Mainland)
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TIANFU-CHEM - Lubiprostone CAS NO.136790-76-6
- FOB Price: USD: 1,000.00-1,000.00 /Kilogram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
- Available Specifications:
1(1-100)Kilogram
- Product Details
Keywords
- Lubiprostone
- 136790-76-6
- C20H32F2O5
Quick Details
- ProName: TIANFU-CHEM - Lubiprostone
- CasNo: 136790-76-6
- Molecular Formula: C20H32F2O5
- Appearance: Solid
- Application: Organic synthesis
- DeliveryTime: PROMPT
- PackAge: IN 25kg drums
- Port: SHANGHAI
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99.0%
- Storage: In Room Temperature
- Transportation: As per MSDS
- LimitNum: 1 Gram
- Heavy metal: N/A
- Grade: Industrial Grade,Food Grade,Pharma Gra...
Superiority
Henan Tianfu Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license.
We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the company is to put quality first and put our customer’s needs first - the satisfaction of our customers is the company's ultimate goal.
Improving product quality and service level is our responsibility, and creating more value for our customer’s is our purpose. We are constantly striving to make Henan Tianfu a leading chemical supplier, and hope to create a better future with you.
Details
Lubiprostone Basic information
Description References
Product Name: Lubiprostone
Synonyms: Lubiprostone API;7-[(1r,4r,6r,9r)-4-(1,1-difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo[4.3.0]non-9-yl]heptanoic acid;lubiprostone;(11a)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid;Ru 0211;C13707;(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid;Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)-
CAS: 136790-76-6
MF: C20H32F2O5
MW: 390.4618864
EINECS:
Product Categories: Inhibitors;Prostaglandin;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs
Mol File: 136790-76-6.mol
Lubiprostone Structure
Lubiprostone Chemical Properties
Melting point 56-59°C
storage temp. -20°C Freezer
Safety Information
MSDS Information
Lubiprostone Usage And Synthesis
Description Marketed under the trade name Amitiza, Lubiprostone is a chloride channel activator which is mainly used for the treatment of idiopathic (due to an unknown cause) chronic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. Lubiprostone is an oral medication approved by the FDA in January 2006.
The mechanism of action of lubiprostone is the same as chloride channel activator. It functions by binding and activating ClC-2 chloride channels in the apical membrane of the gastrointestinal epithelium, which produces an efflux of chloride-rich fluid secretion. The increased amounts of secretions are effective to soften the stool, increase motility, promote spontaneous bowel movements (SBM), and speed up transit of stool in the colon. Therefore, the relevant symptoms, such as abdominal pain and bloating, can be reduced.
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Chemical Properties White Solid
Uses A locally acting chloride channel activator for the treatment of gastrointestinal disorders
Uses Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.
Lubiprostone Preparation Products And Raw materials