TIANFU CHEM--COMBRETASTATIN A-4 CAS NO.117048-59-6

Min.Order: 1 Kilogram
Payment Terms: L/C,T/T,MoneyGram

Product Details

Keywords

COMBRETASTATIN A-4
117048-59-6
COMBRETASTATIN A-4

Quick Details

ProName: TIANFU CHEM--COMBRETASTATIN A-4
CasNo: 117048-59-6
Molecular Formula: C18H20O5
Appearance: Powder
Application: INTERMEDIATE
DeliveryTime: depend on yr quantity
PackAge: bottle/drum or customer's request
Port: shanghai
ProductionCapacity: 10 Kilogram/Month
Purity: 97%
Storage: N/A
Transportation: BY AIR, EXPRESS. OR SEA
LimitNum: 1 Kilogram
Grade: Industrial Grade,Pharma Grade

Superiority

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:

1.Noble Metal Catalysts (Pt.Pd...)

2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

3.OLED intermediates (Fluorene,Carbazole,Boric acid...)

4.Customs Synthesis

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Anyway ,if you need any chemicals from China ,Henan Tianfu can help you

Details

Product Name: COMBRETASTATIN A-4

Synonyms: (Z)-2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenol,3,4,5-Trimethoxy-3hydroxy-4methoxy-(Z)-stilbene,CS-A4;Combrestatin A4( 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol );(Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenol ,98%;2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol;3-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-6-methoxyphenol;5-[(Z)-2-(3,4,5-Trimethoxyphenyl)ethenyl]-2-methoxyphenol;Combretastatin A4;(Z)-CombretastatinA4

CAS: 117048-59-6

MF: C18H20O5

MW: 316.3484

EINECS:

Product Categories: Inhibitors;Combretastatin;Anti-cancer & immunity;API

Mol File: 117048-59-6.mol

COMBRETASTATIN A-4 Structure

COMBRETASTATIN A-4 Chemical Properties

Melting point 84.5-85.5°C

storage temp. Desiccate at -20°C

solubility DMSO: >10mg/mL

color off-white

Merck 14,2494

Safety Information

Hazard Codes T

Risk Statements 23/24/25-41

Safety Statements 26-36/37-39-45

RIDADR UN 2811

HazardClass 6.1

PackingGroup Ⅲ

MSDS Information

COMBRETASTATIN A-4 Usage And Synthesis

Chemical Properties Crystalline Powder

Uses Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site.

Biological Activity Antitumor, antiangiogenic and antimetastatic agent, in vitro and in vivo . Acts by inhibiting tubulin polymerization (IC 50 = 2-3 μ M).

COMBRETASTATIN A-4 Preparation Products And Raw materials

Henan Tianfu Chemical Co., Ltd.