Product Name: Succinic anhydride
Synonyms: Succinic Anhydridc;2,5(3H,4H)-Furandione;5-Furandione,dihydro-2;bernsteinsaureanhydrid;Bernsteinsaure-anhydrid;dihydro-5-furandione;Dihydro-furan-2,5-dione;NCI-C55696
CAS: 108-30-5
MF: C4H4O3
MW: 100.07
EINECS: 203-570-0
Product Categories: Fine chemicals;SuccinicSeries;Heterocycles;Isotope Labelled Compounds;Building Blocks;Carbonyl Compounds;Carboxylic Acid Anhydrides;Chemical Synthesis;Organic Building Blocks
Mol File: 108-30-5.mol
Succinic anhydride Chemical Properties
Melting point  118-120 °C(lit.)
Boiling point  261 °C(lit.)
density  1,572 g/cm3
vapor density  3.5 (vs air)
vapor pressure  1 mm Hg ( 92 °C)
refractive index  1.4688 (estimate)
Fp  157°C
storage temp.  Store at 0-5°C
solubility  62.9g/l Hydrolysis
Specific Gravity 1.2340 (20℃)
PH 2.7 (10g/l, H2O)
Water Solubility  <0.1 g/100 mL at 21 ºC (decomposes)
Sensitive  Moisture Sensitive
Merck  14,8870
BRN  108441
Stability: Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture.
InChIKey RINCXYDBBGOEEQ-UHFFFAOYSA-N
CAS DataBase Reference 108-30-5(CAS DataBase Reference)
NIST Chemistry Reference 2,5-Furandione, dihydro-(108-30-5)
EPA Substance Registry System Succinic anhydride (108-30-5)
Safety Information
Hazard Codes  Xi,Xn
Risk Statements  36/37-22
Safety Statements  25-46
RIDADR  UN 3261 8 / PGII
WGK Germany  1
RTECS  WN0875000
F  21
Autoignition Temperature 480 °C
TSCA  Yes
HS Code  29171990
Hazardous Substances Data 108-30-5(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 1510 mg/kg
Succinic anhydride Usage And Synthesis
Description Succinic anhydride, also called di hydro - 2,5- furandione , is an organic compound with the molecular formula C4H4O3.This colorless solid is the acid anhydride of succinic acid.
Chemical Properties fine white crystalline solid
Uses It was used in the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.It was also used in preparing functionalized oxide surfaces on a chip.
Uses Succinic Anhydride is an acidulant that hydrolyzes very slowly to succinic acid in water. it has thermal stability and a low melting point of 118°c which permits it to be used in products at compara- tively low temperatures. it is used as a leavening acidulant for bak- ing powder.
Application Alkyl succinic anhydride (ASA) is used as a sizing agent or wet strength additive in paper production.
Production Methods The compound is produced from succinic anhydride and hydrogen peroxide . This material must be stabilized by using a dehydrating agent such as disodium sulfate or magnesium sulfate.
Preparation A solution of succinic acid (500 mg, 42 mmol) and triethylamine (1.23 mL, 42 mmol) in anhydrous THF (120 mL) was allowed to react with triphosgene (42 mg, 7.0 mmol) at ice-water temperature for 10 min. The reaction mixture was subsequently stirred for a further 15 min at room temperature. The solution was then filtered, and the filtrate was concentrated to dryness. The residue was crystallized from ethyl acetate to afford the desired product as white crystals (370 mg, 85%).

Product Name: Succinic anhydride
Synonyms: Succinic Anhydridc;2,5(3H,4H)-Furandione;5-Furandione,dihydro-2;bernsteinsaureanhydrid;Bernsteinsaure-anhydrid;dihydro-5-furandione;Dihydro-furan-2,5-dione;NCI-C55696
CAS: 108-30-5
MF: C4H4O3
MW: 100.07
EINECS: 203-570-0
Product Categories: Fine chemicals;SuccinicSeries;Heterocycles;Isotope Labelled Compounds;Building Blocks;Carbonyl Compounds;Carboxylic Acid Anhydrides;Chemical Synthesis;Organic Building Blocks
Mol File: 108-30-5.mol
Succinic anhydride Chemical Properties
Melting point  118-120 °C(lit.)
Boiling point  261 °C(lit.)
density  1,572 g/cm3
vapor density  3.5 (vs air)
vapor pressure  1 mm Hg ( 92 °C)
refractive index  1.4688 (estimate)
Fp  157°C
storage temp.  Store at 0-5°C
solubility  62.9g/l Hydrolysis
Specific Gravity 1.2340 (20℃)
PH 2.7 (10g/l, H2O)
Water Solubility  <0.1 g/100 mL at 21 ºC (decomposes)
Sensitive  Moisture Sensitive
Merck  14,8870
BRN  108441
Stability: Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture.
InChIKey RINCXYDBBGOEEQ-UHFFFAOYSA-N
CAS DataBase Reference 108-30-5(CAS DataBase Reference)
NIST Chemistry Reference 2,5-Furandione, dihydro-(108-30-5)
EPA Substance Registry System Succinic anhydride (108-30-5)
Safety Information
Hazard Codes  Xi,Xn
Risk Statements  36/37-22
Safety Statements  25-46
RIDADR  UN 3261 8 / PGII
WGK Germany  1
RTECS  WN0875000
F  21
Autoignition Temperature 480 °C
TSCA  Yes
HS Code  29171990
Hazardous Substances Data 108-30-5(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 1510 mg/kg
Succinic anhydride Usage And Synthesis
Description Succinic anhydride, also called di hydro - 2,5- furandione , is an organic compound with the molecular formula C4H4O3.This colorless solid is the acid anhydride of succinic acid.
Chemical Properties fine white crystalline solid
Uses It was used in the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.It was also used in preparing functionalized oxide surfaces on a chip.
Uses Succinic Anhydride is an acidulant that hydrolyzes very slowly to succinic acid in water. it has thermal stability and a low melting point of 118°c which permits it to be used in products at compara- tively low temperatures. it is used as a leavening acidulant for bak- ing powder.
Application Alkyl succinic anhydride (ASA) is used as a sizing agent or wet strength additive in paper production.
Production Methods The compound is produced from succinic anhydride and hydrogen peroxide . This material must be stabilized by using a dehydrating agent such as disodium sulfate or magnesium sulfate.
Preparation A solution of succinic acid (500 mg, 42 mmol) and triethylamine (1.23 mL, 42 mmol) in anhydrous THF (120 mL) was allowed to react with triphosgene (42 mg, 7.0 mmol) at ice-water temperature for 10 min. The reaction mixture was subsequently stirred for a further 15 min at room temperature. The solution was then filtered, and the filtrate was concentrated to dryness. The residue was crystallized from ethyl acetate to afford the desired product as white crystals (370 mg, 85%).