TIANFU CHEM--FASUDIL CAS NO.103745-39-7

Min.Order: 1 Kilogram
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Product Details

Keywords

FASUDIL
103745-39-7
FASUDIL

Quick Details

ProName: TIANFU CHEM--FASUDIL
CasNo: 103745-39-7
Molecular Formula: C14H17N3O2S
Appearance: Powder
Application: intermediate
DeliveryTime: depend on yr quantity
PackAge: Aluminium Foil Bag and Paper Drum
Port: shanghai
ProductionCapacity: 100 Kilogram/Month
Purity: 99.5%
Storage: Room temperature
Transportation: By Sea/Air/DHL
LimitNum: 1 Kilogram
Grade: Industrial Grade

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Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:

1.Noble Metal Catalysts (Pt.Pd...)

2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

3.OLED intermediates (Fluorene,Carbazole,Boric acid...)

4.Customs Synthesis

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Details

Product Name: FASUDIL

Synonyms: FASUDIL;1-(5-ISOQUINOLINE-SULFONYL)-HOMOPIPERAZINE;at877;hexahydro-1-(5-isoquinolinylsulfonyl)-1h-4-diazepine;HA-1077 DIHYDROCHLORIDE NOVEL VASODILATO R AGE;HA 1077, DIHYDROCHLORIDE, 99+%;Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine;HA-1077：Eril

CAS: 103745-39-7

MF: C14H17N3O2S

MW: 291.37

EINECS:

Product Categories: Protein Kinase Inhibitors and Activators;Protein Kinase;Signalling;Angiogenesis and Metastasis;Intracellular signaling;APIs;ERIL;Fasudil ada@tuskwei.com sky;18031153937@189.cn;Glutaraldehyde ada@tuskwei.com whatsapp;8618031153937

Mol File: 103745-39-7.mol

FASUDIL Structure

FASUDIL Chemical Properties

storage temp. Store at RT

solubility H2O: >200 mg/mL

form solid

color white

Water Solubility Soluble in water or DMSO

CAS DataBase Reference 103745-39-7(CAS DataBase Reference)

Safety Information

WGK Germany 3

RTECS HM4031166

MSDS Information

FASUDIL Usage And Synthesis

Chemical Properties White Crystalline Solid

Uses vasodilator (cerebral), Ca antagonist

Uses A potent calcium antagonist vasodilator which is considered to act by employing different mechanisms from the usual calcium channel blockers since it inhibits (1) calcium ionophore A23187 induced co ntraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellular space. Also reported to potently inhibit Rho- associated Kinase (ROCK IC50= 10.7 uM).

Biological Activity Cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM). Ca2+ antagonist and vasodilator. Also inhibits proliferation of vascular smooth muscle cells.

Henan Tianfu Chemical Co., Ltd.