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N-Methyl-N-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine CAS NO.101828-21-1
- FOB Price: USD: 15.00-15.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T
- Available Specifications:
1(1-1000)Kilogram
- Product Details
Keywords
- Butenafine
- Butenafine
- 101828-21-1
Quick Details
- ProName: N-Methyl-N-(naphthalen-1-ylmethyl)-1-(...
- CasNo: 101828-21-1
- Molecular Formula: C23H27N
- Appearance: powder
- Application: For Organic synthsis
- DeliveryTime: in stock
- PackAge: As per customer's
- Port: Shanghai,Qingdao
- ProductionCapacity: 1 Metric Ton/Day
- Purity: 98.0% Min
- Storage: Room temperature
- Transportation: To be shipped as non-hazardous chemica...
- LimitNum: 1 Kilogram
- Heavy metal: %
- Grade: Industrial Grade,Pharma Grade
- Water: %
Superiority
Details
Product Name: Butenafine
Synonyms: BUTENAFINE;n-methyl-n-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine;n-(p-tert-butylbenzyl)-n-methyl-1-naphthalenemethylamine;N-methyl-N-(4-methylbenzyl)-N-(1-naphthylmethyl)amine;4-tert-Butylbenzylmethyl 1-naphtylmethylamine;N-(4-tert-Butylbenzyl)-N-methyl-1-naphthalenemethanamine;(4-tert-butylbenzyl)-methyl-(1-naphthylmethyl)amine;1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
CAS: 101828-21-1
MF: C23H27N
MW: 317.47
EINECS:
Product Categories:
Mol File: 101828-21-1.mol
Butenafine Structure
Butenafine Chemical Properties
Melting point 200-202 °C
Boiling point 426.1±14.0 °C(Predicted)
density 1.032±0.06 g/cm3(Predicted)
pka 7.87±0.50(Predicted)
CAS DataBase Reference 101828-21-1(CAS DataBase Reference)
Safety Information
MSDS Information
Butenafine Usage And Synthesis
Uses Butenafine (Mentax) is a synthetic benzylamine antifungal agent, related structurally and pharmacologically to terbinafine. It is thought to act by inhibiting the enzyme squalene 2,3-epoxidase, resulting in decreased ergosterol and corresponding increase in squalene, with subsequent cell membrane permeability alteration and cell death. It is active against dermatophytes, yeast, and Sporothrix.
Butenafine (Mentax)
Definition ChEBI: Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in funga cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
Brand name Lotrimin (Schering); Mentax (Mylan Bertek).