China (Mainland)
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TAINFUCHEM: GDC-0068 CAS NO.1001264-89-6
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,
- Product Details
Keywords
- GDC-0068
- GDC-0068
- 1001264-89-6
Quick Details
- ProName: TAINFUCHEM: GDC-0068
- CasNo: 1001264-89-6
- Molecular Formula: C24H32ClN5O2
- Appearance: white powder
- Application: For Organic Synthesis use
- DeliveryTime: Prompt
- PackAge: As per buyers'
- Port: SHANGHAI,PORT
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99.0%Min
- Storage: In Room Temperature
- Transportation: BY SEA OR AIR
- LimitNum: 1 Kilogram
- Heavy metal: N/M
- Grade: Industrial Grade,Food Grade,Pharma Gra...
- N/M: N/M
Superiority
Product Name: GDC-0068
Synonyms: GDC-0068;GDC-0068(RG7440);RG7440;(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone;Ipatasertib (GDC-0068);Ipatasertib;(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one;(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone Ipatasertib (GDC-0068)
CAS: 1001264-89-6
MF: C24H32ClN5O2
MW: 457.99618
EINECS:
Product Categories: Inhibitor;PI3K/Akt/mTOR;Inhibitors
Mol File: 1001264-89-6.mol
Details
GDC-0068 Chemical Properties
density 1.254
Safety Information
MSDS Information
GDC-0068 Usage And Synthesis
Usage DC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2, and Akt3 with IC50 of 5 nM, 18 nM, and 8 nM, respectively.
Usage (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone is a highly selective AKT inhibitor targeting Akt1 , Akt2 and Akt3. Studies have shown its use in combination with vemurafenib (V118500), have demonstrated therapeutic value in the treatment of hyperproliferative disorders such as cancer.