Product Name: TREHALOSE
Synonyms: D-(+)-TREHALOSE;D-TREHALOSE;(2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-oxybis(2-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol);TREHALOSE(P);ALPHA-D-TREHALOSE;ALPHA,ALPHA-D-TREHALOSE;MYCOSE;TREHALOSE
CAS: 99-20-7
MF: C12H22O11
MW: 342.3
EINECS: 202-739-6
Product Categories: Basic Sugars (Mono & Oligosaccharides);Biochemistry;Disaccharides;Sugars;Natural Plant Extract;Sweeteners
Mol File: 99-20-7.mol

TREHALOSE Chemical Properties
Melting point  203 °C
Boiling point  397.76°C (rough estimate)
density  1.5800
refractive index  197 ° (C=7, H2O)
RTECS  LZ5776770
solubility  Soluble in water; very slightly soluble in ethanol (95%); practically insoluble in ether.
pka 12.53±0.70(Predicted)
form  Powder
color  White to Off-white
Water Solubility  Soluble in water.
Sensitive  Hygroscopic
Merck  14,9580
CAS DataBase Reference 99-20-7(CAS DataBase Reference)
EPA Substance Registry System Trehalose (99-20-7)
Safety Information
Hazard Codes  Xi
Risk Statements  38
Safety Statements  37/39-26
TSCA  Yes
HS Code  29400090

TREHALOSE Usage And Synthesis
Description Trehalose is a nonreducing disaccharide in which the two glucose molecules are linked together in an α,α-1,1-glycosidic linkage. α,α-trehalose is the only anomer of trehalose, which has been isolated from and biosynthesized in living organisms. This sugar is present in a wide variety of organisms, including bacteria, yeast, fungi, insects, invertebrates, and lower and higher plants, where it may serve as a source of energy and carbon.  It can be used as a stabilizer and protectant of proteins and membranes: protection from dehydration; protection from damage by oxygen radicals (against oxidation); protection from cold; as a sensing compound and/or growth regulator; as a structural component of the bacterial cell wall. Trehalose is used in the biopharmaceutical preservation of labile protein drugs and in the cryopreservation of human cells. It is used as an ingredient for dried and processed food, and as an artificial sweetener, with a relative sweetness of 40-45% that of sucrose. Several safety studies on trehalose have been evaluated by JECFA, 2001 and allocated an ADI of ‘not specified’. Trehalose is approved in Japan, Korea, Taiwan, and UK. Trehalose could be possibly used in an eye drop solution to against corneal damage due to desiccation (dry eye syndrome).

Product Name: TREHALOSE
Synonyms: D-(+)-TREHALOSE;D-TREHALOSE;(2R,2'R,3S,3'S,4S,4'S,5R,5'R,6R,6'R)-6,6'-oxybis(2-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol);TREHALOSE(P);ALPHA-D-TREHALOSE;ALPHA,ALPHA-D-TREHALOSE;MYCOSE;TREHALOSE
CAS: 99-20-7
MF: C12H22O11
MW: 342.3
EINECS: 202-739-6
Product Categories: Basic Sugars (Mono & Oligosaccharides);Biochemistry;Disaccharides;Sugars;Natural Plant Extract;Sweeteners
Mol File: 99-20-7.mol

TREHALOSE Chemical Properties
Melting point  203 °C
Boiling point  397.76°C (rough estimate)
density  1.5800
refractive index  197 ° (C=7, H2O)
RTECS  LZ5776770
solubility  Soluble in water; very slightly soluble in ethanol (95%); practically insoluble in ether.
pka 12.53±0.70(Predicted)
form  Powder
color  White to Off-white
Water Solubility  Soluble in water.
Sensitive  Hygroscopic
Merck  14,9580
CAS DataBase Reference 99-20-7(CAS DataBase Reference)
EPA Substance Registry System Trehalose (99-20-7)
Safety Information
Hazard Codes  Xi
Risk Statements  38
Safety Statements  37/39-26
TSCA  Yes
HS Code  29400090

TREHALOSE Usage And Synthesis
Description Trehalose is a nonreducing disaccharide in which the two glucose molecules are linked together in an α,α-1,1-glycosidic linkage. α,α-trehalose is the only anomer of trehalose, which has been isolated from and biosynthesized in living organisms. This sugar is present in a wide variety of organisms, including bacteria, yeast, fungi, insects, invertebrates, and lower and higher plants, where it may serve as a source of energy and carbon.  It can be used as a stabilizer and protectant of proteins and membranes: protection from dehydration; protection from damage by oxygen radicals (against oxidation); protection from cold; as a sensing compound and/or growth regulator; as a structural component of the bacterial cell wall. Trehalose is used in the biopharmaceutical preservation of labile protein drugs and in the cryopreservation of human cells. It is used as an ingredient for dried and processed food, and as an artificial sweetener, with a relative sweetness of 40-45% that of sucrose. Several safety studies on trehalose have been evaluated by JECFA, 2001 and allocated an ADI of ‘not specified’. Trehalose is approved in Japan, Korea, Taiwan, and UK. Trehalose could be possibly used in an eye drop solution to against corneal damage due to desiccation (dry eye syndrome).