Product Name: Triethylamine trihydrofluoride
Synonyms: MEC-82;HF 37% IN TRIETHYLAMINE;HF;HYDROGEN FLUORIDE TRIETHYLAMINE;TRIETHYLAMINE TRIHYDROFLUORIDE;TRIETHYLAMINE TRISHYDROFLUORIDE;TRIETHYLAMINE TRIS(HYDROGEN FLUORIDE);Triethylamin-trihydrofluoride
CAS: 73602-61-6
MF: C6H18F3N
MW: 161.21
EINECS: 277-550-5
Product Categories: Fluorinating Reagents;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Fluorination;Halogenation;Nucleophilic Fluorinating Reagents;Synthetic Organic Chemistry
Mol File: 73602-61-6.mol

Triethylamine trihydrofluoride Chemical Properties
Melting point  -29--27°C
Boiling point  70 °C15 mm Hg(lit.)
density  0.989 g/mL at 25 °C(lit.)
refractive index  n20/D 1.3915(lit.)
Fp  190 °F
storage temp.  Keep Cold
form  Liquid
color  Clear yellow to brown
Specific Gravity 0.989
PH 3 (H2O, 20℃)(saturated aqueous solution)
Water Solubility  soluble
Sensitive  Hygroscopic
BRN  5522945
CAS DataBase Reference 73602-61-6(CAS DataBase Reference)
EPA Substance Registry System Ethanamine, N,N-diethyl-, trihydrofluoride (73602-61-6)
Safety Information
Hazard Codes  T+,T,C,Xi,F
Risk Statements  26/27/28-35-36/37/38-20/21/22-11
Safety Statements  26-36/37/39-45-7/9-36/37-36-61-29-16-3
RIDADR  UN 3265 8/PG 2
WGK Germany  3
Hazard Note  Corrosive
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29211910

Triethylamine trihydrofluoride Usage And Synthesis
Application
The t-butyldimethylsilyl (TBDMS) group is the most widely used 2'-OH protection in synthesis of oligoribonucleotides. The TBDMS-group became much used particularly after it was combined with phosphoroamidite methodology and was also the choice when H-phosphonate based RNA-synthesis was introduced. Removal of TBDMS-protection is most commonly done with 1 M tetrabutylammonium fluoride (TBAF) in tetrahydrofuran (THF). These conditions has proven efficient.

Chemical Properties clear yellow liquid

Product Name: Triethylamine trihydrofluoride
Synonyms: MEC-82;HF 37% IN TRIETHYLAMINE;HF;HYDROGEN FLUORIDE TRIETHYLAMINE;TRIETHYLAMINE TRIHYDROFLUORIDE;TRIETHYLAMINE TRISHYDROFLUORIDE;TRIETHYLAMINE TRIS(HYDROGEN FLUORIDE);Triethylamin-trihydrofluoride
CAS: 73602-61-6
MF: C6H18F3N
MW: 161.21
EINECS: 277-550-5
Product Categories: Fluorinating Reagents;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Fluorination;Halogenation;Nucleophilic Fluorinating Reagents;Synthetic Organic Chemistry
Mol File: 73602-61-6.mol

Triethylamine trihydrofluoride Chemical Properties
Melting point  -29--27°C
Boiling point  70 °C15 mm Hg(lit.)
density  0.989 g/mL at 25 °C(lit.)
refractive index  n20/D 1.3915(lit.)
Fp  190 °F
storage temp.  Keep Cold
form  Liquid
color  Clear yellow to brown
Specific Gravity 0.989
PH 3 (H2O, 20℃)(saturated aqueous solution)
Water Solubility  soluble
Sensitive  Hygroscopic
BRN  5522945
CAS DataBase Reference 73602-61-6(CAS DataBase Reference)
EPA Substance Registry System Ethanamine, N,N-diethyl-, trihydrofluoride (73602-61-6)
Safety Information
Hazard Codes  T+,T,C,Xi,F
Risk Statements  26/27/28-35-36/37/38-20/21/22-11
Safety Statements  26-36/37/39-45-7/9-36/37-36-61-29-16-3
RIDADR  UN 3265 8/PG 2
WGK Germany  3
Hazard Note  Corrosive
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29211910

Triethylamine trihydrofluoride Usage And Synthesis
Application
The t-butyldimethylsilyl (TBDMS) group is the most widely used 2'-OH protection in synthesis of oligoribonucleotides. The TBDMS-group became much used particularly after it was combined with phosphoroamidite methodology and was also the choice when H-phosphonate based RNA-synthesis was introduced. Removal of TBDMS-protection is most commonly done with 1 M tetrabutylammonium fluoride (TBAF) in tetrahydrofuran (THF). These conditions has proven efficient.

Chemical Properties clear yellow liquid