Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:

1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis

Our advantage:

1. Higest quality and good package
2.Fast delivery
3.Better payment term
4.Fast response to customer within 6 hours
5.Good business credit in Europe ,US ,Japan ,Korea

Anyway ,if you need any chemicals from China ,Henan Tianfu can help you

Product Name: Mitoxantrone
Synonyms: MITOXANTRONE;1,4-dihydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedi;1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]-anthracene-9,10-dione;MitoxantroneBase;Mitoxantrone Hcl 70476-82-3 / Base;PharmasubstanceEP4;1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione;NSC-27983
CAS: 65271-80-9
MF: C22H28N4O6
MW: 444.48
EINECS: 1533716-785-6
Product Categories: Pharmaceutical material and intermeidates;Intermediates & Fine Chemicals;Pharmaceuticals;Anti-cancer&immunity;Inhibitors
Mol File: 65271-80-9.mol
Mitoxantrone Structure
Mitoxantrone Chemical Properties
Melting point  170-1740C
Boiling point  554.47°C (rough estimate)
density  1.3049 (rough estimate)
refractive index  1.6500 (estimate)
storage temp.  -20°C Freezer
pka pKa 5.99 (Uncertain);8.13 (Uncertain)
CAS DataBase Reference 65271-80-9(CAS DataBase Reference)
Safety Information
Hazard Codes  T,T+
Risk Statements  46-61-26/27/28
Safety Statements  53-36/37/39-45-22
WGK Germany  3
RTECS  CB5748500
MSDS Information
Mitoxantrone Usage And Synthesis
Chemical Properties Dark Blue Crystalline Solid
Uses A DNA intercalating drug. Inhibits DNA synthesis. Used as an anti-cancer agent
Uses Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent.
Indications Mitoxantrone (Novantrone) is a synthetic anthraquinone that is structurally and mechanistically related to the anthracyclines. It intercalates with DNA and produces single- strand DNA breakage. It is cross-resistant with doxorubicin in multidrug-resistant cells and in patients who have failed to respond to doxorubicin therapy.
Mitoxantrone is active against breast carcinomas, leukemias, and lymphomas. Its antitumor efficacy in patients with breast cancer is slightly lower than that of doxorubicin. Its major toxicity is myelosuppression; mucositis and diarrhea also may occur. Mitoxantrone produces less nausea, alopecia, and cardiac toxicity than does doxorubicin.
Brand name Novantrone (Serono).
Veterinary Drugs and Treatments Mitoxantrone may be useful in the treatment of several neoplastic diseases in dogs and cats, including lymphosarcoma mammary adenocarcinoma, squamous cell carcinoma, renal adenocarcinoma, fibroid sarcoma, thyroid or transitional cell carcinomas, and hemangiopericytoma.
Because renal clearance of the drug is minimal (10%), it may be administered to cats with renal insufficiency much more safely than doxorubicin.