Product Name: 19-Norethindrone acetate
Synonyms: acetic acid (17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl) ester;17-acetyloxy(17-alpha)-19-norpregn-4-estren-17-beta-ol-acetate-3-one;17-Acetyloxy(17alpha)-19-norpregn-4-estren-17beta-ol-acetate-3-one;17alpha-Ethinyl-19-nortestosterone 17beta-acetate;17alpha-Ethinyl-19-nortestosterone acetate;17-alpha-ethinyl-19-nortestosterone-17-beta-acetate;17-alpha-ethinyl-19-nortestosteroneacetate;17-alpha-ethynyl-17-beta-acetoxy-19-norandrost-4-en-3-one
CAS: 51-98-9
MF: C22H28O3
MW: 340.46
EINECS: 200-132-0
Product Categories: Active Pharmaceutical Ingredients;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;AYGESTIN
Mol File: 51-98-9.mol

19-Norethindrone acetate Chemical Properties
Melting point  161-162°
Boiling point  416.25°C (rough estimate)
density  1.1236 (rough estimate)
refractive index  -34 ° (C=1, Dioxane)
storage temp.  2-8°C
solubility  Practically insoluble in water, freely soluble in methylene chloride, soluble in alcohol.
form  neat
color  Crystals from Me2CO/hexane
Water Solubility  3.162mg/L(10 ºC)
Merck  14,6697
InChIKey IMONTRJLAWHYGT-ZCPXKWAGSA-N
CAS DataBase Reference 51-98-9(CAS DataBase Reference)
NIST Chemistry Reference Norethindrone acetate(51-98-9)
Safety Information
Hazard Codes  Xn
Risk Statements  40-48
Safety Statements  36/37
WGK Germany  3
RTECS  RC8965000
HS Code  29372390
Toxicity dlt-mus-orl 1120 mg/kg/4W MUREAV 26,535,74

19-Norethindrone acetate Usage And Synthesis
Chemical Properties White Solid
Uses Progesteron. Norethindrone and acetate in combination with estrogen as contraceptive (oral). It is reasonably anticipated to be a human carcinogen.
Uses Oral contraceptive (in combination with estrogen)
Definition ChEBI: A 3-oxo Delta4-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester.
Brand name Aygestin (Duramed); Norlutate (Parke-Davis).
Safety Profile Suspected carcinogen with experimental tumorigenic data. Human reproductive effects by ingestion and implant routes: menstrual cycle changes, postpartum effects, and changes in fertility. A human teratogen by an unspecified route with developmental abnormalities of the urogenital system. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. Used in the treatment of menstrual dsorders and uterine bleedmg.

Product Name: 19-Norethindrone acetate
Synonyms: acetic acid (17-ethynyl-13-methyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl) ester;17-acetyloxy(17-alpha)-19-norpregn-4-estren-17-beta-ol-acetate-3-one;17-Acetyloxy(17alpha)-19-norpregn-4-estren-17beta-ol-acetate-3-one;17alpha-Ethinyl-19-nortestosterone 17beta-acetate;17alpha-Ethinyl-19-nortestosterone acetate;17-alpha-ethinyl-19-nortestosterone-17-beta-acetate;17-alpha-ethinyl-19-nortestosteroneacetate;17-alpha-ethynyl-17-beta-acetoxy-19-norandrost-4-en-3-one
CAS: 51-98-9
MF: C22H28O3
MW: 340.46
EINECS: 200-132-0
Product Categories: Active Pharmaceutical Ingredients;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;AYGESTIN
Mol File: 51-98-9.mol

19-Norethindrone acetate Chemical Properties
Melting point  161-162°
Boiling point  416.25°C (rough estimate)
density  1.1236 (rough estimate)
refractive index  -34 ° (C=1, Dioxane)
storage temp.  2-8°C
solubility  Practically insoluble in water, freely soluble in methylene chloride, soluble in alcohol.
form  neat
color  Crystals from Me2CO/hexane
Water Solubility  3.162mg/L(10 ºC)
Merck  14,6697
InChIKey IMONTRJLAWHYGT-ZCPXKWAGSA-N
CAS DataBase Reference 51-98-9(CAS DataBase Reference)
NIST Chemistry Reference Norethindrone acetate(51-98-9)
Safety Information
Hazard Codes  Xn
Risk Statements  40-48
Safety Statements  36/37
WGK Germany  3
RTECS  RC8965000
HS Code  29372390
Toxicity dlt-mus-orl 1120 mg/kg/4W MUREAV 26,535,74

19-Norethindrone acetate Usage And Synthesis
Chemical Properties White Solid
Uses Progesteron. Norethindrone and acetate in combination with estrogen as contraceptive (oral). It is reasonably anticipated to be a human carcinogen.
Uses Oral contraceptive (in combination with estrogen)
Definition ChEBI: A 3-oxo Delta4-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester.
Brand name Aygestin (Duramed); Norlutate (Parke-Davis).
Safety Profile Suspected carcinogen with experimental tumorigenic data. Human reproductive effects by ingestion and implant routes: menstrual cycle changes, postpartum effects, and changes in fertility. A human teratogen by an unspecified route with developmental abnormalities of the urogenital system. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. Used in the treatment of menstrual dsorders and uterine bleedmg.