50-50-0 Estradiol benzoate CAS NO.50-50-0
- FOB Price: USD: 500.00-500.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T
- Available Specifications:
A(10-150)Kilogram
- Product Details
Keywords
- 50-50-0 Estradiol benzoate
- 50-50-0 Estradiol benzoate
- 50-50-0 Estradiol benzoate
Quick Details
- ProName: 50-50-0 Estradiol benzoate
- CasNo: 50-50-0
- Molecular Formula: C25H28O3
- Appearance: Powder
- Application: Organic Chemicals
- DeliveryTime: according to client's demand quantity
- PackAge: as requested
- Port: SHANGHAI
- ProductionCapacity: 100 Metric Ton/Day
- Purity: 99%
- Storage: room temperature
- Transportation: BY SEA
- LimitNum: 1 Kilogram
- Heavy metal: 10ppm
- Grade: Industrial Grade,Pharma Grade
- Transportation: LCL
Superiority
Product Name: Estradiol benzoate
Synonyms: 3-Benzoyloxy-17β-estrol;Estradiol Benzoate (250 mg) (AS);Estradiol Benzoate, Powder, BP;17-Estradiol-d3 3-Benzoate;(8R,9S,13S,14S,17S)-17-hydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl benzoate;(1S,10R,11S,14R,15S)-5-hydroxy-15-Methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-yl benzoate;Estra-1,3,5(10)-triene-3,17-diol(17b)-, 3-benzoate;Estradiol Benzoate (250 mg)
CAS: 50-50-0
MF: C25H28O3
MW: 376.49
EINECS: 200-043-7
Product Categories: API;progestogen estrogen;ACCUTANE;Hormone Drugs;Hormone;Biochemistry;Hydroxysteroids;Steroids
Mol File: 50-50-0.mol
Estradiol benzoate Chemical Properties
Melting point 191-198 °C(lit.)
alpha D25 +58 to +63° (c = 2 in dioxane)
Boiling point 465.03°C (rough estimate)
density 1.0493 (rough estimate)
refractive index 1.5460 (estimate)
storage temp. 2-8°C
solubility Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol.
form neat
Water Solubility 0.4mg/L(25 ºC)
Merck 3703
BRN 3107526
CAS DataBase Reference 50-50-0(CAS DataBase Reference)
NIST Chemistry Reference Estradiol benzoate(50-50-0)
Safety Information
Hazard Codes T
Risk Statements 60-61-40
Safety Statements 53-22-36/37/39-45
WGK Germany 3
RTECS KG4050000
F 8
HS Code 29372319
Hazardous Substances Data 50-50-0(Hazardous Substances Data)
Estradiol benzoate Usage And Synthesis
Chemical Properties White solid
Uses antiacne, antineoplastic
Uses Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.
Definition ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.
Clinical Use Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.
Safety Profile Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.
Details
Product Name: Estradiol benzoate
Synonyms: 3-Benzoyloxy-17β-estrol;Estradiol Benzoate (250 mg) (AS);Estradiol Benzoate, Powder, BP;17-Estradiol-d3 3-Benzoate;(8R,9S,13S,14S,17S)-17-hydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl benzoate;(1S,10R,11S,14R,15S)-5-hydroxy-15-Methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-yl benzoate;Estra-1,3,5(10)-triene-3,17-diol(17b)-, 3-benzoate;Estradiol Benzoate (250 mg)
CAS: 50-50-0
MF: C25H28O3
MW: 376.49
EINECS: 200-043-7
Product Categories: API;progestogen estrogen;ACCUTANE;Hormone Drugs;Hormone;Biochemistry;Hydroxysteroids;Steroids
Mol File: 50-50-0.mol
Estradiol benzoate Chemical Properties
Melting point 191-198 °C(lit.)
alpha D25 +58 to +63° (c = 2 in dioxane)
Boiling point 465.03°C (rough estimate)
density 1.0493 (rough estimate)
refractive index 1.5460 (estimate)
storage temp. 2-8°C
solubility Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol.
form neat
Water Solubility 0.4mg/L(25 ºC)
Merck 3703
BRN 3107526
CAS DataBase Reference 50-50-0(CAS DataBase Reference)
NIST Chemistry Reference Estradiol benzoate(50-50-0)
Safety Information
Hazard Codes T
Risk Statements 60-61-40
Safety Statements 53-22-36/37/39-45
WGK Germany 3
RTECS KG4050000
F 8
HS Code 29372319
Hazardous Substances Data 50-50-0(Hazardous Substances Data)
Estradiol benzoate Usage And Synthesis
Chemical Properties White solid
Uses antiacne, antineoplastic
Uses Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.
Definition ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.
Clinical Use Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.
Safety Profile Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.