China (Mainland)
Assessedsupplier
Metoprolol CAS NO.37350-58-6
- FOB Price: USD: 30.00-30.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,
- Available Specifications:
1(1-1000)Kilogram
- Product Details
Keywords
- Metoprolol
- Metoprolol
- 37350-58-6
Quick Details
- ProName: Metoprolol
- CasNo: 37350-58-6
- Molecular Formula: C15H25NO3
- Appearance: Powder
- Application: intermediate
- DeliveryTime: in stock
- PackAge: as per buyers
- Port: Shanghai,Qingdao
- ProductionCapacity: 1 Metric Ton/Day
- Purity: 99%
- Storage: R.T.
- Transportation: by air/sea
- LimitNum: 1 Kilogram
- Heavy metal: %
- Grade: Industrial Grade,Pharma Grade
- Water: %
Superiority
Details
Product Name: Metoprolol
Synonyms: 1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol;1-(Isopropylamino)-3-[p-(2-methoxyethyl)phenoxy]-2-propanol;2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-;2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (±;2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (.+/-.)-;CGP 2175;cgp2175;H-23/96
CAS: 37350-58-6
MF: C15H25NO3
MW: 267.36
EINECS: 253-483-7
Product Categories: Cardiovascular
Mol File: 37350-58-6.mol
Metoprolol Structure
Metoprolol Chemical Properties
Boiling point 410.55°C (rough estimate)
density 1.0281 (rough estimate)
refractive index 1.5000 (estimate)
CAS DataBase Reference 37350-58-6(CAS DataBase Reference)
NIST Chemistry Reference Metoprolol(37350-58-6)
Safety Information
Hazardous Substances Data 37350-58-6(Hazardous Substances Data)
MSDS Information
Metoprolol Usage And Synthesis
Uses Antiadrenergic (β-receptor).
Brand name Lopressor (Novartis).
Metabolism The pharmacokinetic profile of metoprolol (Lopressor) is similar to that of propranolol. Metoprolol is readily and rapidly absorbed after oral administration and is subject to a significant amount of first-pass metabolism by the liver. Curiously, the duration of metoprolol’s action is longer than one would predict from its plasma half-life, which ranges from 0.5 to 2.5 hours. The degree of binding of metoprolol to plasma proteins is modest (10%). The extensive distribution of metoprolol to the lungs and kidney is typical of a moderately lipophilic drug. Metoprolol undergoes considerable metabolism;only 3 to 10% of an administered dose is recovered as unchanged drug.The metabolites are essentially inactive as -receptor blocking agents and are eliminated primarily by renal excretion. Small amounts of the drug are present in the feces.