Product Name: Fumaric acid
Synonyms: Butenedioic acid, (E)-;femanumber:2488;fumaric;Kyselina fumarova;kyselinafumarova;kyselinafumarova(czech);NSC-2752;trans-1,2-ethenedicarboxylicacid
CAS: 110-17-8
MF: C4H4O4
MW: 116.07
EINECS: 203-743-0
Product Categories: INORGANIC & ORGANIC CHEMICALS;FOOD ADDITIVES;Organic Building Blocks;Allium cepa (Onion);Nutrition Research;Panax ginseng;Phytochemicals by Plant (Food/Spice/Herb);reagent;standard substance;Food additive and acidulant;CONSTRUCTION;Intermediates;Food & Feed ADDITIVES;Substrates;C1 to C5;Carbonyl Compounds;Carboxylic Acids;Alphabetical Listings;E-F;Flavors and Fragrances;Companion Products and ReagentsCancer Research;Chemopreventive Agents;Insect Platform;Multidrug Resistance;Phase II Enzyme Inducers;Phase II Enzyme InducersCancer Research;Serum-free Media;Food & Flavor Additives;Aliphatics;Building Blocks;C1 to C5;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis
Mol File: 110-17-8.mol

Fumaric acid Chemical Properties
Melting point  298-300 °C (subl.)(lit.)
Boiling point  137.07°C (rough estimate)
density  1.62
vapor pressure  1.7 mm Hg ( 165 °C)
FEMA  2488 | FUMARIC ACID
refractive index  1.5260 (estimate)
Fp  230 °C
storage temp.  Store below +30°C.
solubility  95% ethanol: soluble0.46g/10 mL, clear, colorless
form  Fine Crystalline Powder
pka 3.02, 4.38(at 25℃)
color  White
PH 2.1 (4.9g/l, H2O, 20℃)
explosive limit 40%
Water Solubility  0.63 g/100 mL (25 ºC)
JECFA Number 618
Merck  14,4287
BRN  605763
Stability: Stable at room temperature. Decomposes at around 230 C. Incompatible with strong oxidizing agents, bases, reducing agents. Combustible.
InChIKey VZCYOOQTPOCHFL-OWOJBTEDSA-N
CAS DataBase Reference 110-17-8(CAS DataBase Reference)
NIST Chemistry Reference Fumaric acid(110-17-8)
EPA Substance Registry System Fumaric acid (110-17-8)
Safety Information
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
RIDADR  UN 9126
WGK Germany  1
RTECS  LS9625000
Autoignition Temperature 375 °C
TSCA  Yes
HS Code  29171900
Hazardous Substances Data 110-17-8(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 9300 mg/kg LD50 dermal Rabbit 20000 mg/kg

Fumaric acid Usage And Synthesis
Description Fumaric acid is an important kind of organic chemical raw materials as well as the intermediate of fine chemical products. Meanwhile, it is also an important kind of derivatives of maleic anhydride, being widely used in food, coatings, resins and plasticizers. In the food industry, fumaric acid, used as souring agent, can be applied to soft drinks, western-style wine, cold drinks, fruit juice concentrate, canned fruit, pickles and ice cream. As an acidic substance used as solid beverage gas production agent, it has excellent bubble durability with delicate product organization.
Fumaric acid has been used as a food acidulant since 1946. As a food additive, it is used as an acidity regulator and can be denoted by the E number E297. Chemically it is an unsaturated dicarbonic acid and is part of the citric acid cycle.
Fumaric acid is a common food additive included in many processed foods to keep them stable and to add tartness. The substance has a more sour flavor than citric acid, another common food additive. Fumaric acid occurs naturally in fumitory, bolete mushrooms, lichen and Iceland moss. As an additive, fumaric acid is produced synthetically, mainly from malic acid from apples. Fumaric acid as an additive is regulated under the Codex Alimentarius General Standard for Food Additives (GSFA), a collection of internationally recognized standards.The U.S. Food and Drug Administration considers it safe.

Product Name: Fumaric acid
Synonyms: Butenedioic acid, (E)-;femanumber:2488;fumaric;Kyselina fumarova;kyselinafumarova;kyselinafumarova(czech);NSC-2752;trans-1,2-ethenedicarboxylicacid
CAS: 110-17-8
MF: C4H4O4
MW: 116.07
EINECS: 203-743-0
Product Categories: INORGANIC & ORGANIC CHEMICALS;FOOD ADDITIVES;Organic Building Blocks;Allium cepa (Onion);Nutrition Research;Panax ginseng;Phytochemicals by Plant (Food/Spice/Herb);reagent;standard substance;Food additive and acidulant;CONSTRUCTION;Intermediates;Food & Feed ADDITIVES;Substrates;C1 to C5;Carbonyl Compounds;Carboxylic Acids;Alphabetical Listings;E-F;Flavors and Fragrances;Companion Products and ReagentsCancer Research;Chemopreventive Agents;Insect Platform;Multidrug Resistance;Phase II Enzyme Inducers;Phase II Enzyme InducersCancer Research;Serum-free Media;Food & Flavor Additives;Aliphatics;Building Blocks;C1 to C5;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis
Mol File: 110-17-8.mol

Fumaric acid Chemical Properties
Melting point  298-300 °C (subl.)(lit.)
Boiling point  137.07°C (rough estimate)
density  1.62
vapor pressure  1.7 mm Hg ( 165 °C)
FEMA  2488 | FUMARIC ACID
refractive index  1.5260 (estimate)
Fp  230 °C
storage temp.  Store below +30°C.
solubility  95% ethanol: soluble0.46g/10 mL, clear, colorless
form  Fine Crystalline Powder
pka 3.02, 4.38(at 25℃)
color  White
PH 2.1 (4.9g/l, H2O, 20℃)
explosive limit 40%
Water Solubility  0.63 g/100 mL (25 ºC)
JECFA Number 618
Merck  14,4287
BRN  605763
Stability: Stable at room temperature. Decomposes at around 230 C. Incompatible with strong oxidizing agents, bases, reducing agents. Combustible.
InChIKey VZCYOOQTPOCHFL-OWOJBTEDSA-N
CAS DataBase Reference 110-17-8(CAS DataBase Reference)
NIST Chemistry Reference Fumaric acid(110-17-8)
EPA Substance Registry System Fumaric acid (110-17-8)
Safety Information
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
RIDADR  UN 9126
WGK Germany  1
RTECS  LS9625000
Autoignition Temperature 375 °C
TSCA  Yes
HS Code  29171900
Hazardous Substances Data 110-17-8(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 9300 mg/kg LD50 dermal Rabbit 20000 mg/kg

Fumaric acid Usage And Synthesis
Description Fumaric acid is an important kind of organic chemical raw materials as well as the intermediate of fine chemical products. Meanwhile, it is also an important kind of derivatives of maleic anhydride, being widely used in food, coatings, resins and plasticizers. In the food industry, fumaric acid, used as souring agent, can be applied to soft drinks, western-style wine, cold drinks, fruit juice concentrate, canned fruit, pickles and ice cream. As an acidic substance used as solid beverage gas production agent, it has excellent bubble durability with delicate product organization.
Fumaric acid has been used as a food acidulant since 1946. As a food additive, it is used as an acidity regulator and can be denoted by the E number E297. Chemically it is an unsaturated dicarbonic acid and is part of the citric acid cycle.
Fumaric acid is a common food additive included in many processed foods to keep them stable and to add tartness. The substance has a more sour flavor than citric acid, another common food additive. Fumaric acid occurs naturally in fumitory, bolete mushrooms, lichen and Iceland moss. As an additive, fumaric acid is produced synthetically, mainly from malic acid from apples. Fumaric acid as an additive is regulated under the Codex Alimentarius General Standard for Food Additives (GSFA), a collection of internationally recognized standards.The U.S. Food and Drug Administration considers it safe.